Description of the need
I've just implemented hook_theme_registry_alter() in a custom block and checked the registry content to see long list of variables, including for unused layout templates. Disabling them on admin/structure/layouts/settings freed registry from unnecessary content and even-though human eyes might not notice, definitely made things slightly faster.
Proposed solution
I believe Backdrop must be shipped as performant as possible, so I suggest to disable all unused layout templates by default. Users can easily enable them if they need additional templates.
Additionally, we could add a pointer link on pages like admin/structure/layouts/manage/dashboard/configure as shown below:

Recent comments
So the implication is that another module is causing the trouble. Now for the slow process of elimination... Sounds plausible. And good luck with digging...
How to troubleshoot interactive image cropping modules?
I’ve just set up a clean install in MAMP and Focal Point works fine. *sighs So the implication is that another module is causing the trouble. Now for the slow process of elimination...
How to troubleshoot interactive image cropping modules?
Here’s the edit screen with the Focal Point instructions below: If I click on the Preview link, I get this: And no errors in the console.
How to troubleshoot interactive image cropping modules?