Description of the need
Now that config values can be overridden via settings.php, we've created a system that can also be very confusing for admins and editors. When a value is overridden it appears as though the forms are broken.
For example, when CSS aggregation is set to FALSE in settings.php, visiting the form at admin/config/development/performance appears as usual, but when I attempt to check the box for "Aggregate and compress CSS files" and submit the form, it submits as usual, and the message The configuration options have been saved. is printed to the screen. However, when I scroll down to the checkbox for "Aggregate and compress CSS files" it remains unchecked.
Proposed solution
@herbdool posted a proof of concept PR that contained some interface components that indicated when a config value was overridden. I'm not sure how far this proof of concept is from a workable solution, but I really liked where it was heading:

Additional information
This is a follow up to https://github.com/backdrop/backdrop-issues/issues/2805
Recent comments
There is a Drupal 7 contrib module that "lets the administrator see all administration pages in her preferred language" and which could be ported to Backdrop: https://www.drupal.org/project/...
Allow admin to select admin language seperate from front end language (multilingual)
@stpaultim – You're right: my approach affects also the main menu. I guess, because menus are also considered as user interface (not as content). @findlabnet – If I didn't miss anything,...
Allow admin to select admin language seperate from front end language (multilingual)
Go to the account edit of the desired user. On the horizontal tab below "Region and Language," select "English" or another language. WFM.
Allow admin to select admin language seperate from front end language (multilingual)